David J Sharp | MANIFOLD Lab

Traumatic brain injury: a comparison of diffusion and volumetric magnetic resonance imaging measures

Fri, 01 Jan 2021 00:00:00 +0000

Authors: Niall J Bourke, Maria Yanez Lopez, Peter O Jenkins, Sara De Simoni, James H Cole, Pete Lally, Emma-Jane Mallas, Hui Zhang, David J Sharp

DOI: https://doi.org/10.1093/braincomms/fcab006

Diffuse axonal injury predicts neurodegeneration after moderate–severe traumatic brain injury

Wed, 01 Jan 2020 00:00:00 +0000

Authors: Neil S N Graham, Amy Jolly, Karl Zimmerman, Niall J Bourke, Gregory Scott, James H Cole, Jonathan M Schott, David J Sharp

DOI: https://doi.org/10.1093/brain/awaa316

Nonlinear biomarker interactions in conversion from mild cognitive impairment to Alzheimer's disease

Wed, 01 Jan 2020 00:00:00 +0000

Authors: Sebastian G. Popescu, Alex Whittington, Roger N. Gunn, Paul M. Matthews, Ben Glocker, David J Sharp, James H Cole

DOI: https://doi.org/10.1002/hbm.25133

Stratifying drug treatment of cognitive impairments after traumatic brain injury using neuroimaging

Tue, 01 Jan 2019 00:00:00 +0000

Authors: Peter O Jenkins, Sara De Simoni, Niall J Bourke, Jessica Fleminger, Gregory Scott, David J Towey, William Svensson, Sameer Khan, Maneesh C Patel, Richard Greenwood, Daniel Friedland, Adam Hampshire, James H Cole, David J Sharp

DOI: https://doi.org/10.1093/brain/awz149

Validation of a Novel Multivariate Method of Defining HIV-Associated Cognitive Impairment

Tue, 01 Jan 2019 00:00:00 +0000

Authors: Jonathan Underwood, Davide De Francesco, James H Cole, Matthan W A Caan, Rosan A van Zoest, Ben A Schmand, David J Sharp, Caroline A Sabin, Peter Reiss, Alan Winston, P Reiss, F W N M Wit, J Schouten, K W Kooij, R A van Zoest, B C Elsenga, F R Janssen, M Heidenrijk, W Zikkenheiner, M van der Valk, N A Kootstra, A M Harskamp-Holwerda, I Maurer, M M Mangas Ruiz, A F Girigorie, J Villaudy, E Frankin, A Pasternak, B Berkhout, T van der Kuyl, P Portegies, B A Schmand, G J Geurtsen, J A ter Stege, M Klein Twennaar, C B L M Majoie, M W A Caan, T Su, K Weijer, P H L T Bisschop, A Kalsbeek, M Wezel, I Visser, H G Ruhé, C Franceschi, P Garagnani, C Pirazzini, M Capri, F Dall’Olio, M Chiricolo, S Salvioli, J Hoeijmakers, J Pothof, M Prins, M Martens, S Moll, J Berkel, M Totté, S Kovalev, M Gisslén, D Fuchs, H Zetterberg, A Winston, J Underwood, L McDonald, M Stott, K Legg, A Lovell, O Erlwein, N Doyle, C Kingsley, D J Sharp, R Leech, J H Cole, S Zaheri, M M J Hillebregt, Y M C Ruijs, D P Benschop, D Burger, M de Graaff-Teulen, G Guaraldi, A Bürkle, T Sindlinger, M Moreno-Villanueva, A Keller, C Sabin, D de Francesco, C Libert, S Dewaele, Marta Boffito, Paddy Mallon, Frank Post, Caroline Sabin, Memory Sachikonye, Alan Winston, Jane Anderson, David Asboe, Marta Boffito, Lucy Garvey, Paddy Mallon, Frank Post, Anton Pozniak, Caroline Sabin, Memory Sachikonye, Jaime Vera, Ian Williams, Alan Winston, Frank Post, Lucy Campbell, Selin Yurdakul, Sara Okumu, Louise Pollard, Ian Williams, Damilola Otiko, Laura Phillips, Rosanna Laverick, Martin Fisher, Amanda Clarke, Jaime Vera, Andrew Bexley, Celia Richardson, Paddy Mallon, Alan Macken, Bijan Ghavani-Kia, Joanne Maher, Maria Byrne, Ailbhe Flaherty, Jane Anderson, Sifiso Mguni, Rebecca Clark, Rhiannon Nevin-Dolan, Sambasivarao Pelluri, Margaret Johnson, Nnenna Ngwu, Nargis Hemat, Martin Jones, Anne Carroll, Andrew Whitehouse, Laura Burgess, Daphne Babalis, Alan Winston, Lucy Garvey, Jonathan Underwood, Matthew Stott, Linda McDonald, Marta Boffito, David Asboe, Anton Pozniak, Chris Higgs, Elisha Seah, Stephen Fletcher, Michelle Anthonipillai, Ashley Moyes, Katie Deats, Irtiza Syed, Clive Matthews

DOI: https://doi.org/10.1093/ofid/ofz198

Dopaminergic abnormalities following traumatic brain injury

Mon, 01 Jan 2018 00:00:00 +0000

Authors: Peter O Jenkins, Sara De Simoni, Niall J Bourke, Jessica Fleminger, Gregory Scott, David J Towey, William Svensson, Sameer Khan, Maneesh Patel, Richard Greenwood, James H Cole, David J Sharp

DOI: https://doi.org/10.1093/brain/awx357

No Evidence for Accelerated Aging-Related Brain Pathology in Treated Human Immunodeficiency Virus: Longitudinal Neuroimaging Results From the Comorbidity in Relation to AIDS (COBRA) Project

Mon, 01 Jan 2018 00:00:00 +0000

Authors: James H Cole, Matthan W A Caan, Jonathan Underwood, Davide De Francesco, Rosan A van Zoest, Ferdinand W N M Wit, Henk J M M Mutsaerts, Rob Leech, Gert J Geurtsen, Peter Portegies, Charles B L M Majoie, Maarten F Schim van der Loeff, Caroline A Sabin, Peter Reiss, Alan Winston, David J Sharp

DOI: https://doi.org/10.1093/cid/cix1124

Spatial patterns of progressive brain volume loss after moderate-severe traumatic brain injury

Mon, 01 Jan 2018 00:00:00 +0000

Authors: James H Cole, Amy Jolly, Sara de Simoni, Niall Bourke, Maneesh C Patel, Gregory Scott, David J Sharp

DOI: https://doi.org/10.1093/brain/awx354

Altered caudate connectivity is associated with executive dysfunction after traumatic brain injury

Sun, 01 Jan 2017 00:00:00 +0000

Authors: Sara De Simoni, Peter O Jenkins, Niall J Bourke, Jessica J Fleminger, Peter J Hellyer, Amy E Jolly, Maneesh C Patel, James H Cole, Robert Leech, David J Sharp

DOI: https://doi.org/10.1093/brain/awx309

Minocycline reduces chronic microglial activation after brain trauma but increases neurodegeneration

Sun, 01 Jan 2017 00:00:00 +0000

Authors: Gregory Scott, Henrik Zetterberg, Amy Jolly, James H Cole, Sara De Simoni, Peter O Jenkins, Claire Feeney, David R Owen, Anne Lingford-Hughes, Oliver Howes, Maneesh C Patel, Anthony P Goldstone, Roger N Gunn, Kaj Blennow, Paul M Matthews, David J Sharp

DOI: https://doi.org/10.1093/brain/awx339

Structural Brain Abnormalities in Successfully Treated HIV Infection: Associations With Disease and Cerebrospinal Fluid Biomarkers

Sun, 01 Jan 2017 00:00:00 +0000

Authors: Rosan A van Zoest, Jonathan Underwood, Davide De Francesco, Caroline A Sabin, James H Cole, Ferdinand W Wit, Matthan W A Caan, Neeltje A Kootstra, Dietmar Fuchs, Henrik Zetterberg, Charles B L M Majoie, Peter Portegies, Alan Winston, David J Sharp, Magnus Gisslén, Peter Reiss, P Reiss, A Winston, F W Wit, M Prins, M F Schim van der Loeff, J Schouten, B Schmand, G J Geurtsen, D J Sharp, M W A Caan, C Majoie, J Villaudy, B Berkhout, N A Kootstra, M Gisslén, A Pasternak, C A Sabin, G Guaraldi, A Bürkle, C Libert, C Franceschi, A Kalsbeek, E Fliers, J Hoeijmakers, J Pothof, M van der Valk, P H Bisschop, P Portegies, S Zaheri, D Burger, P Reiss, A Winston, F W Wit, J H Cole, M W A Caan, J Villaudy, N A Kootstra, M F Schim van der Loeff, M Gisslén, C A Sabin, A Bürkle, W Zikkenheiner, P Reiss, W Zikkenheiner, F W Wit, F R Janssen, A Winston, F W Wit, J Underwood, J Schouten, K W Kooij, R A van Zoest, N Doyle, M Prins, M Schim van der Loeff, P Portegies, B A Schmand, G J Geurtsen, E Verheij, S O Verboeket, B C Elsenga, M van der Valk, S Zaheri, M M J Hillebregt, Y M C Ruijs, D P Benschop, L Tembo, L McDonald, M Stott, K Legg, A Lovell, O Erlwein, C Kingsley, P Norsworthy, S Mullaney, T Kruijer, L del Grande, V Olthof, G R Visser, L May, F Verbraak, N Demirkaya, I Visser, G Guaraldi, D J Sharp, M W A Caan, J H Cole, C B L M Majoie, T Su, R Leech, J Huguet, J Villaudy, E Frankin, A Pasternak, B Berkhout, A van der Kuyl, K Weijer, E Siteur-Van Rijnstra, N A Kootstra, M Gisslén, A M Harskamp-Holwerda, I Maurer, M M Mangas Ruiz, A F Girigorie, B Boeser-Nunnink, A Kalsbeek, P H L T Bisschop, D Burger, M de Graaff-Teulen, J Hoeijmakers, J Pothof, C Libert, S Dewaele, C Franceschi, P Garagnani, C Pirazzini, M Capri, F Dall’Olio, M Chiricolo, S Salvioli, D Fuchs, H Zetterberg, D Weber, T Grune, E H J M Jansen, C A Sabin, D De Francesco, F W Wit, A Bürkle, T Sindlinger, S Oehlke, W Zikkenheiner, R A van Zoest

DOI: https://doi.org/10.1093/infdis/jix553