Brain Age

Brain-age is associated with progression to dementia in memory clinic patients

**Background**: Biomarkers for the early detection of dementia risk hold promise for better disease monitoring and targeted interventions. However, most biomarker studies, particularly in neuroimaging, have analysed artificially ‘clean’ research …

Thalamic white matter macrostructure and subnuclei volumes in Parkinson’s disease depression

Thalamic changes in Parkinson's disease depression

Accurate brain‐age models for routine clinical MRI examinations

Brain age can be predicted accurately from 2D T2-weighted or DWI scans.

Multimodality neuroimaging brain-age in UK biobank: relationship to biomedical, lifestyle, and cognitive factors

Multi-modality MRI used to predict chronological age in healthy people in the UK Biobank.

Nonlinear biomarker interactions in conversion from Mild Cognitive Impairment to Alzheimer's disease

Multi-modality MRI and PET used to predict progression to dementia from mild cognitive impairment in ADNI.

BARCODE

Predicting risk of dementia in adults with subjective or mild cognitive impairment using the brain-age paradigm.

ENIGMA Brain Age

James Cole chairs the ENIGMA Brain Age working group.

Motor Neurone Disease

Predicting disease progression in motor neurone disease

Multimodality MRI brain age prediction

Using the UK Biobank to predict brain age from multiple modalities of MRI data, including structural, diffusion and functional scans.